Connecting you with life-saving harm reduction resources including needle exchanges, naloxone distribution, HIV testing, and more.
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Colorado authorizes syringe exchange programs statewide by law. Naloxone access runs through Senate Bill 15-053, which lets the chief medical officer of the Colorado Department of Public Health and Environment (CDPHE) issue standing orders to pharmacies and harm reduction organizations on request, rather than one single statewide order; community members who receive naloxone this way can pass it on to a family member, friend, or anyone else in a position to help, without criminal or civil liability. Colorado's 911 Good Samaritan law grants immunity from prosecution to anyone who reports an overdose in good faith, whether to police, 911, or a medical provider. Fentanyl test strips are legal, distributed no-cost through CDPHE and local public health agencies, with liability protections further expanded under a 2022 law (HB22-1326).
The Colorado Consortium for Prescription Drug Abuse Prevention, formed in 2013, coordinates work across harm reduction, naloxone, prescription monitoring, and treatment access statewide. The Colorado Opioid Abatement Council oversees 19 regional councils that direct opioid settlement money toward treatment, recovery, harm reduction, and prevention across the state's 64 counties, and the Harm Reduction Action Center in Denver partners directly with CDPHE to integrate Hepatitis C treatment into syringe access services.
With 19 regional councils each making their own local decisions, program availability and focus can vary meaningfully by region; the Colorado Consortium's harm reduction work group is a good place to start looking.
Last reviewed September 2026 by Penny Beach, PRS.
Recently added agencies in Colorado
Showing 8 recently added agencies in Colorado out of 55 total — search a city above to narrow it down
Local listings for these cities. The number is how many locations are listed.
Find agencies that offer these critical services
Safe syringe exchange programs that reduce disease transmission and provide a connection to care.
No Cost or low-cost naloxone (Narcan) distribution to reverse opioid overdoses.
Confidential testing for HIV and Hepatitis C with connections to treatment.
Basic wound care services to prevent infections and complications.
Fentanyl test strips and drug checking services to reduce overdose risk.
Find harm reduction agencies in your state. See the national overview
Harm reduction is a set of practical strategies and ideas aimed at reducing negative consequences associated with drug use. It is also a movement for social justice built on a belief in, and respect for, the rights of people who use drugs.
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